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Zenit PRO

The information to be found in this section is intended for the exclusive use of healthcare professionals.

 

Driving standardization through automation

Integrated slide processing that changes the way IFA is performed

A. Menarini Diagnostics brought engineering and capability to the lab by simply developing the sole system that ensures the complete preparation of the IFA slide, from serum dilution to coverslipping, minimizing operator intervention all along a high-volume testing procedure.

The Zenit PRO automated liquid handling system eliminates the inconsistency of human intervention, maximizing the accuracy of the overall IFA process and ensuring accurate sample dispensation, controlled incubation conditions and efficient washing.

  • Up to 160 tubes: 8 racks with 20 tubes each
  • Up to 288 cuvettes: 3 x 96-well consumable plates, 1.2 ml volume
  • Up to 20 slots for controls
  • Up to 9 slots for conjugate and mounting medium
  • Up to 4 slots for diluent


Advanced and powerful information management for results that matter

As smart and simple as you want it to be

Zenit PRO offers powerful analytics and a simple and intuitive user interface that simplify workflows and enable meaningful analysis of results to efficiently achieve diagnostic goals even from the most challenging assays.

Simply powerful

The system can process and scan a number of cellular substrates and provides whole well digitization of any IFA Zenit test: it performs the analysis on the whole well and not just on a limited number of pre-defined images only partially covering the area of interest.

This feature offers several advantages:

  • As the number of counted and analyzed cells is fairly large (greater than 3.000 for each well), the results are more reliable and consistent
  • Results are robust even in the presence of microbubbles or damaged areas in the well
  • High sensitivity thanks to the possibility to adjust cell count and cell identification to detect rare patterns or a pattern displayed by a few cells only

Full screen view of the IFA test:
The digitized image is displayed and can be navigated with the virtual microscope tool that allows the user to have a broad view of the substrate at multiple magnifications.


From assay to answer

Results are interpreted and validated by the operator, using the touch screen monitor, or remotely at another station within the laboratory using a powerful yet intuitive software interface. Customizable views facilitate navigation.

1. Multiview
for visualization and analysis of multiple wells of the same patient’s sample on the same slide (different dilutions)
2. Send to LIS
Sends results directly to LIS as soon as each well is validated and before the session is archived
3. Patient info Shows the Patient card with relevant info
4. Results Gives an indication of the Slide/well and performs an automatic diagnosis (Pos/Unc/Neg) giving an Index value as result
5. Patterns The list of all the possible patterns associated to the specific substrate analysed is shown
6. Extra tests
To select additional IFA/non IFA tests

History/Patient
To evaluate on the screen multiple tests (digital wells) of the same patient (different dilutions, different tests, both of the same session or from the archive)

Smart analysis software for meaningful data

Add confidence to your results

The system includes the automatic classification of positive/negative results for Zenit ANA HEp-2 tests and the identification of a number of cellular patterns even in mixed cases. The software measures the intensity of fluorescence for each positive test and provides a pattern suggestion based on a wide database of reference images used to train a state of the art classifier.

Add confidence to your results

The system includes the automatic classification of positive/negative results for Zenit ANA HEp-2 tests and the identifìcation of nine different HEp-2 patterns: Homogeneous, Fine speckled, Coarse speckled, Nucleola, Centromere, Few nucleolar dots, Multiple nuclear dots, Ribosomal-like, Mitochondrial-like. Patterns can be recognized even in mixed cases. The software measures the intensity of fluorescence for each positive test and provides a pattern suggestion based on a wide database of reference images used to train a state of the art classifìer. The system includes the automatic classification of positive/negative results and Pattern recognition (c-ANCA, p-ANCA, Others) for Zenit ANCA tests and the automatic positive/negative classification for Zenit nDNA Crithidia Luciliae tests.