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Biomonitoring

The Zenit product range includes all of the most innovative

technologies for detecting everything relevant to the diagnosis

and monitoring of autoimmune diseases.

…and so muchmore

The development of biological drugs (i.e., antibo-

dies with unique characteristics and specificities)

is an important advance in the treatment of inflam-

matory conditions such as rheumatoid diseases

and inflammatory bowel diseases. However, ef-

ficacy can be hampered by the development

of anti-drug antibodies (ADAs). It is important to

monitor the levels of these so-called biologicals

during treatment. Most biologicals are relatively

expensive, and drug dose, response and efficacy

should be monitored on an individual basis.

Awareness of these issues has lead to the deve-

lopment of drug monitoring regimens to optimize

therapy both clinically and economically.

A. Menarini Diagnostics offers several monitoring

tools, reagents and services developed to measure

drug activity and ADAs.

Celiac disease and type 1 diabetes are autoimmune

disorders affecting the lining of the small intestine

in celiac disease and pancreatic beta-cells in type

1 diabetes.

Celiac disease is far more common in people with

type 1 diabetes than in the general population –

as many as 10% of children with type 1 diabetes

test positive for the antibodies that indicate celiac

disease, compared with only one 1% of children in

the general population. Moreover, a growing body

of research suggests type 1 diabetes is triggered by

exposure to gluten, the protein linked to celiac di-

sease, supporting the theory that the two disorders

share common genetic causes.

We are proud to offer an easy range of PCR end-

point kits, to detect the alleles associated to celiac,

ankylosing spondylitis and type 1 diabetes.

Optimizingtreatmentswithbiologicals? A. MenariniDiagnosticshas thebest solutionfor you.